Claritin (loratadine) is one of the antihistamines most often considered acceptable during pregnancy, and large studies have not linked it to birth defects. Major bodies including ACOG and the CDC generally regard second-generation antihistamines like loratadine as reasonable options for allergy symptoms when treatment is needed. As with any medicine in pregnancy, the safest choice is to confirm with your own provider before starting.
Claritin is the brand name for loratadine, a second-generation (non-drowsy) antihistamine used for hay fever and allergy symptoms like sneezing, itching, and a runny nose. It is sold over the counter in both the US and UK. Some products labelled Claritin-D also contain the decongestant pseudoephedrine, which is treated differently in pregnancy and should not be assumed to carry the same safety profile.
Loratadine has been studied in thousands of pregnancies, and reviews by groups such as the CDC's Treating for Two program have not found a meaningful increase in birth defects. The NHS lists loratadine as an antihistamine that can be used in pregnancy, and ACOG notes that certain second-generation antihistamines are among the preferred options when allergy treatment is needed. Because it is non-sedating, many providers favour it over older antihistamines like diphenhydramine for daytime use.
Non-medication steps, such as avoiding triggers and using saline sprays, are often tried first, especially in the first trimester. If medication is needed, cetirizine (Zyrtec) and loratadine are the two second-generation antihistamines most commonly recommended. Avoid combination Claritin-D products with a decongestant unless your provider approves them, since pseudoephedrine has separate cautions in early pregnancy, and always use the standard dose rather than more.